BDBM50211158 (R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-2-phenylacetamide::CHEMBL425827

SMILES: C[C@@H](N(CCN(C)C)C(=O)Cc1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1

InChI Key: InChIKey=PYPFATXWJIPBRX-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50211158 ((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...) Show SMILES C[C@@H](N(CCN(C)C)C(=O)Cc1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C28H29FN4O2/c1-20(32(18-17-31(2)3)26(34)19-21-9-5-4-6-10-21)27-30-25-12-8-7-11-24(25)28(35)33(27)23-15-13-22(29)14-16-23/h4-16,20H,17-19H2,1-3H3/t20-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
					More data for this Ligand-Target Pair