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BDBM50211230 CHEMBL3948087

SMILES: CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCNCc3ccc(F)c(OC)c3)cc12

InChI Key: InChIKey=TYIFHIPHFGFPNC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211230   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein norA


(Staphylococcus aureus)		BDBM50211230
PNG
(CHEMBL3948087)
Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCNCc3ccc(F)c(OC)c3)cc12
Show InChI InChI=1S/C30H33FN2O4/c1-4-36-30(34)29-21(2)33(20-22-9-6-5-7-10-22)27-14-12-24(18-25(27)29)37-16-8-15-32-19-23-11-13-26(31)28(17-23)35-3/h5-7,9-14,17-18,32H,4,8,15-16,19-20H2,1-3H3
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.83E+3n/an/an/an/an/an/a



University of Perugia

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus 1199B NorA assessed as inhibition of ethidium bromide efflux measured after 5 mins by fluorometric method

J Med Chem 60: 517-523 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01281
BindingDB Entry DOI: 10.7270/Q2D79DKR
More data for this
Ligand-Target Pair