BDBM50211237 CHEMBL3929394
SMILES: OC(C1CCCCC1)(C1CCCCC1)c1cnn(n1)C(=O)N1CCCCC1Cc1ccccc1
InChI Key: InChIKey=LPDBAMMMZZZFNO-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211237 (CHEMBL3929394) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human)) | BDBM50211237 (CHEMBL3929394) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s... | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair |