Found 3 hits for monomerid = 50211577 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50211577
(CHEMBL229036 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1cccc[n+]1[O-])NCC(=O)OC1CCCCC1 Show InChI InChI=1S/C30H40ClN5O5/c31-23-12-11-21(18-32)22(17-23)19-34-29(38)27-10-6-15-35(27)30(39)26(14-13-24-7-4-5-16-36(24)40)33-20-28(37)41-25-8-2-1-3-9-25/h4-5,7,11-12,16-17,25-27,33H,1-3,6,8-10,13-15,18-20,32H2,(H,34,38)/t26-,27+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50211577
(CHEMBL229036 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1cccc[n+]1[O-])NCC(=O)OC1CCCCC1 Show InChI InChI=1S/C30H40ClN5O5/c31-23-12-11-21(18-32)22(17-23)19-34-29(38)27-10-6-15-35(27)30(39)26(14-13-24-7-4-5-16-36(24)40)33-20-28(37)41-25-8-2-1-3-9-25/h4-5,7,11-12,16-17,25-27,33H,1-3,6,8-10,13-15,18-20,32H2,(H,34,38)/t26-,27+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50211577
(CHEMBL229036 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCc1cccc[n+]1[O-])NCC(=O)OC1CCCCC1 Show InChI InChI=1S/C30H40ClN5O5/c31-23-12-11-21(18-32)22(17-23)19-34-29(38)27-10-6-15-35(27)30(39)26(14-13-24-7-4-5-16-36(24)40)33-20-28(37)41-25-8-2-1-3-9-25/h4-5,7,11-12,16-17,25-27,33H,1-3,6,8-10,13-15,18-20,32H2,(H,34,38)/t26-,27+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |