Found 3 hits for monomerid = 50211586 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50211586
((s)-4-(2-aminomethyl-5-chloro-benzylcarbamoyl)-4-[...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@H](CCC(O)=O)NC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccccc1 |w:22.33| Show InChI InChI=1S/C29H34ClN5O7S/c30-23-10-9-21(17-31)22(16-23)18-32-28(38)25(13-14-27(36)37)33-29(39)26(12-11-24-8-4-5-15-35(24)40)34-43(41,42)19-20-6-2-1-3-7-20/h1-10,15-16,25-26,34H,11-14,17-19,31H2,(H,32,38)(H,33,39)(H,36,37)/t25-,26?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50211586
((s)-4-(2-aminomethyl-5-chloro-benzylcarbamoyl)-4-[...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@H](CCC(O)=O)NC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccccc1 |w:22.33| Show InChI InChI=1S/C29H34ClN5O7S/c30-23-10-9-21(17-31)22(16-23)18-32-28(38)25(13-14-27(36)37)33-29(39)26(12-11-24-8-4-5-15-35(24)40)34-43(41,42)19-20-6-2-1-3-7-20/h1-10,15-16,25-26,34H,11-14,17-19,31H2,(H,32,38)(H,33,39)(H,36,37)/t25-,26?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50211586
((s)-4-(2-aminomethyl-5-chloro-benzylcarbamoyl)-4-[...)Show SMILES NCc1ccc(Cl)cc1CNC(=O)[C@H](CCC(O)=O)NC(=O)C(CCc1cccc[n+]1[O-])NS(=O)(=O)Cc1ccccc1 |w:22.33| Show InChI InChI=1S/C29H34ClN5O7S/c30-23-10-9-21(17-31)22(16-23)18-32-28(38)25(13-14-27(36)37)33-29(39)26(12-11-24-8-4-5-15-35(24)40)34-43(41,42)19-20-6-2-1-3-7-20/h1-10,15-16,25-26,34H,11-14,17-19,31H2,(H,32,38)(H,33,39)(H,36,37)/t25-,26?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Curacyte Discovery GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 17: 3322-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.105 BindingDB Entry DOI: 10.7270/Q2NG4Q9K |
More data for this Ligand-Target Pair | |