BDBM50211688 5-{[4'-(2-furyl)-4,5'-bipyrimidin-2'-yl]amino}-1-methylpyridin-2(1H)-one::CHEMBL438306

SMILES: Cn1cc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)ccc1=O

InChI Key: InChIKey=ZTVPMYBJPZDOKZ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50211688 (5-{[4'-(2-furyl)-4,5'-bipyrimidin-2'-yl]amino}-1-m...) Show SMILES Cn1cc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)ccc1=O Show InChI InChI=1S/C18H14N6O2/c1-24-10-12(4-5-16(24)25)22-18-20-9-13(14-6-7-19-11-21-14)17(23-18)15-3-2-8-26-15/h2-11H,1H3,(H,20,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A2B receptor expressed in HEK293 cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50211688 (5-{[4'-(2-furyl)-4,5'-bipyrimidin-2'-yl]amino}-1-m...) Show SMILES Cn1cc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)ccc1=O Show InChI InChI=1S/C18H14N6O2/c1-24-10-12(4-5-16(24)25)22-18-20-9-13(14-6-7-19-11-21-14)17(23-18)15-3-2-8-26-15/h2-11H,1H3,(H,20,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [2H]NECA from human A3 receptor expressed in HeLa cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50211688 (5-{[4'-(2-furyl)-4,5'-bipyrimidin-2'-yl]amino}-1-m...) Show SMILES Cn1cc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)ccc1=O Show InChI InChI=1S/C18H14N6O2/c1-24-10-12(4-5-16(24)25)22-18-20-9-13(14-6-7-19-11-21-14)17(23-18)15-3-2-8-26-15/h2-11H,1H3,(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human A2A receptor expressed in HeLa cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50211688 (5-{[4'-(2-furyl)-4,5'-bipyrimidin-2'-yl]amino}-1-m...) Show SMILES Cn1cc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)ccc1=O Show InChI InChI=1S/C18H14N6O2/c1-24-10-12(4-5-16(24)25)22-18-20-9-13(14-6-7-19-11-21-14)17(23-18)15-3-2-8-26-15/h2-11H,1H3,(H,20,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in CHO cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair