BDBM50212161 7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol::CHEMBL250300
SMILES: Oc1ccc-2c(OCc3c(C=C)c4cc(O)ccc4nc-23)c1
InChI Key: InChIKey=SDQIIVSWOGDEKO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50212161 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Estrogen-related receptor alpha
(Homo sapiens (Human)) | BDBM50212161
(7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)Show InChI InChI=1S/C18H13NO3/c1-2-12-14-7-10(20)4-6-16(14)19-18-13-5-3-11(21)8-17(13)22-9-15(12)18/h2-8,20-21H,1,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068 BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this Ligand-Target Pair | |
Estrogen-related receptor beta
(Homo sapiens (Human)) | BDBM50212161
(7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)Show InChI InChI=1S/C18H13NO3/c1-2-12-14-7-10(20)4-6-16(14)19-18-13-5-3-11(21)8-17(13)22-9-15(12)18/h2-8,20-21H,1,9H2 | PDB MMDB
Reactome pathway KEGG
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 526 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human ERbeta |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068 BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this Ligand-Target Pair | |