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SMILES: CCN1C(=O)C(C)(C)Oc2cc(C)c(cc12)-c1cc(ccc1OC(F)(F)F)C(\C)=C\C(O)=O

InChI Key: InChIKey=HJTWCLJBRWHWTA-JLHYYAGUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212264   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))		BDBM50212264
PNG
(3-(3-(4-ethyl-2,2,7-trimethyl-3-oxo-3,4-dihydro-2H...)
Show SMILES CCN1C(=O)C(C)(C)Oc2cc(C)c(cc12)-c1cc(ccc1OC(F)(F)F)C(\C)=C\C(O)=O
Show InChI InChI=1S/C24H24F3NO5/c1-6-28-18-12-16(14(3)9-20(18)32-23(4,5)22(28)31)17-11-15(13(2)10-21(29)30)7-8-19(17)33-24(25,26)27/h7-12H,6H2,1-5H3,(H,29,30)/b13-10+
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Article
PubMed
n/an/an/an/a 61.2n/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Activity at RXRalpha by GAL4DNA cotransfection assay

Bioorg Med Chem Lett 17: 3497-503 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.047
BindingDB Entry DOI: 10.7270/Q2FQ9W93
More data for this
Ligand-Target Pair