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SMILES: CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1ccc(\C=C\C(O)=O)o1

InChI Key: InChIKey=HCCSLXKEGONRAM-VQHVLOKHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212281   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))		BDBM50212281
PNG
(3-(5-(1-ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrah...)
Show SMILES CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1ccc(\C=C\C(O)=O)o1
Show InChI InChI=1S/C21H23NO4/c1-5-22-17-11-15(18-8-6-14(26-18)7-9-20(24)25)13(2)10-16(17)21(3,4)12-19(22)23/h6-11H,5,12H2,1-4H3,(H,24,25)/b9-7+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Activity at RXRalpha by GAL4DNA cotransfection assay

Bioorg Med Chem Lett 17: 3497-503 (2007)


Article DOI: 10.1016/j.bmcl.2007.01.047
BindingDB Entry DOI: 10.7270/Q2FQ9W93
More data for this
Ligand-Target Pair