BDBM50212367 CHEMBL541895::threo-1-aza-3alpha-methyl-5-phenyl[4.4.0]decane hydrochloride

SMILES: C[C@H]1C[C@@H]([C@H]2CCCCN2C1)c1ccccc1

InChI Key: InChIKey=KVDDHSOWSOEYMM-NUEKZKHPSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50212367 (CHEMBL541895 | threo-1-aza-3alpha-methyl-5-phenyl[...) Show SMILES C[C@H]1C[C@@H]([C@H]2CCCCN2C1)c1ccccc1 Show InChI InChI=1S/C16H23N/c1-13-11-15(14-7-3-2-4-8-14)16-9-5-6-10-17(16)12-13/h2-4,7-8,13,15-16H,5-6,9-12H2,1H3/t13-,15+,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatum				J Med Chem 50: 2718-31 (2007) Article DOI: 10.1021/jm061354p BindingDB Entry DOI: 10.7270/Q2Q81DXB
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50212367 (CHEMBL541895 | threo-1-aza-3alpha-methyl-5-phenyl[...) Show SMILES C[C@H]1C[C@@H]([C@H]2CCCCN2C1)c1ccccc1 Show InChI InChI=1S/C16H23N/c1-13-11-15(14-7-3-2-4-8-14)16-9-5-6-10-17(16)12-13/h2-4,7-8,13,15-16H,5-6,9-12H2,1H3/t13-,15+,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrum				J Med Chem 50: 2718-31 (2007) Article DOI: 10.1021/jm061354p BindingDB Entry DOI: 10.7270/Q2Q81DXB
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50212367 (CHEMBL541895 | threo-1-aza-3alpha-methyl-5-phenyl[...) Show SMILES C[C@H]1C[C@@H]([C@H]2CCCCN2C1)c1ccccc1 Show InChI InChI=1S/C16H23N/c1-13-11-15(14-7-3-2-4-8-14)16-9-5-6-10-17(16)12-13/h2-4,7-8,13,15-16H,5-6,9-12H2,1H3/t13-,15+,16+/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	694	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissue				J Med Chem 50: 2718-31 (2007) Article DOI: 10.1021/jm061354p BindingDB Entry DOI: 10.7270/Q2Q81DXB
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50212367 (CHEMBL541895 | threo-1-aza-3alpha-methyl-5-phenyl[...) Show SMILES C[C@H]1C[C@@H]([C@H]2CCCCN2C1)c1ccccc1 Show InChI InChI=1S/C16H23N/c1-13-11-15(14-7-3-2-4-8-14)16-9-5-6-10-17(16)12-13/h2-4,7-8,13,15-16H,5-6,9-12H2,1H3/t13-,15+,16+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatum				J Med Chem 50: 2718-31 (2007) Article DOI: 10.1021/jm061354p BindingDB Entry DOI: 10.7270/Q2Q81DXB
					More data for this Ligand-Target Pair