BDBM50212393 CHEMBL229220::abyssinoflavanone VII
SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(cc(-[#6]-[#6](-[#8])-[#6](-[#6])=[#6])c1-[#8])-[#6@@H]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])cc2-[#8]-1
InChI Key: InChIKey=FZUJHUDJFJCWMT-BPARTEKVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM50212393 (CHEMBL229220 | abyssinoflavanone VII) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of human recombinant PTP1B | J Nat Prod 70: 1039-42 (2007) Article DOI: 10.1021/np060477+ BindingDB Entry DOI: 10.7270/Q2KH0P5K | |||||||||||
More data for this Ligand-Target Pair |