BDBM50212405 3-(3-(1-ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(2,2,2-trifluoroethoxy)phenyl)propanoic acid::CHEMBL400894

SMILES: CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(CCC(O)=O)ccc1OCC(F)(F)F

InChI Key: InChIKey=RLYZOZMMCSBBJZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50212405 (3-(3-(1-ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrah...) Show SMILES CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(CCC(O)=O)ccc1OCC(F)(F)F Show InChI InChI=1S/C25H28F3NO4/c1-5-29-20-12-17(15(2)10-19(20)24(3,4)13-22(29)30)18-11-16(7-9-23(31)32)6-8-21(18)33-14-25(26,27)28/h6,8,10-12H,5,7,9,13-14H2,1-4H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	70.2	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Activity at RXRalpha by GAL4DNA cotransfection assay				Bioorg Med Chem Lett 17: 3491-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.049 BindingDB Entry DOI: 10.7270/Q2T153B1
					More data for this Ligand-Target Pair