BDBM50212415 3-(3-(1-isopropyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(2,2,2-trifluoroethoxy)phenyl)propanoic acid::CHEMBL410399

SMILES: CC(C)N1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(CCC(O)=O)ccc1OCC(F)(F)F

InChI Key: InChIKey=VWYFKXPNPXDHME-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50212415 (3-(3-(1-isopropyl-4,4,6-trimethyl-2-oxo-1,2,3,4-te...) Show SMILES CC(C)N1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(CCC(O)=O)ccc1OCC(F)(F)F Show InChI InChI=1S/C26H30F3NO4/c1-15(2)30-21-12-18(16(3)10-20(21)25(4,5)13-23(30)31)19-11-17(7-9-24(32)33)6-8-22(19)34-14-26(27,28)29/h6,8,10-12,15H,7,9,13-14H2,1-5H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	36.5	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Activity at RXRalpha by GAL4DNA cotransfection assay				Bioorg Med Chem Lett 17: 3491-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.049 BindingDB Entry DOI: 10.7270/Q2T153B1
					More data for this Ligand-Target Pair