BDBM50212422 2-(3-(1-ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(2,2,2-trifluoroethoxy)phenyl)cyclopropanecarboxylic acid::CHEMBL246210

SMILES: CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(ccc1OCC(F)(F)F)C1CC1C(O)=O

InChI Key: InChIKey=HMXAWPKQULWZCR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50212422 (2-(3-(1-ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrah...) Show SMILES CCN1C(=O)CC(C)(C)c2cc(C)c(cc12)-c1cc(ccc1OCC(F)(F)F)C1CC1C(O)=O |w:28.30,30.34| Show InChI InChI=1S/C26H28F3NO4/c1-5-30-21-11-16(14(2)8-20(21)25(3,4)12-23(30)31)18-9-15(17-10-19(17)24(32)33)6-7-22(18)34-13-26(27,28)29/h6-9,11,17,19H,5,10,12-13H2,1-4H3,(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Activity at RXRalpha by GAL4DNA cotransfection assay				Bioorg Med Chem Lett 17: 3491-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.049 BindingDB Entry DOI: 10.7270/Q2T153B1
					More data for this Ligand-Target Pair