BDBM50212439 (3aR,4R,9aS,E)-4-(2-(5-(3-chlorophenyl)pyridin-2-yl)vinyl)-7,8-difluoro-3a,4,9,9a-tetrahydronaphtho[2,3-c]furan-1(3H)-one::CHEMBL232348

SMILES: Fc1ccc2[C@H](\C=C\c3ccc(cn3)-c3cccc(Cl)c3)[C@H]3COC(=O)[C@H]3Cc2c1F

InChI Key: InChIKey=VMWGFDICCUXJAO-WAMAQVDTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50212439 ((3aR,4R,9aS,E)-4-(2-(5-(3-chlorophenyl)pyridin-2-y...) Show SMILES Fc1ccc2[C@H](\C=C\c3ccc(cn3)-c3cccc(Cl)c3)[C@H]3COC(=O)[C@H]3Cc2c1F Show InChI InChI=1S/C25H18ClF2NO2/c26-16-3-1-2-14(10-16)15-4-5-17(29-12-15)6-7-19-18-8-9-23(27)24(28)20(18)11-21-22(19)13-31-25(21)30/h1-10,12,19,21-22H,11,13H2/b7-6+/t19-,21-,22+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1				Bioorg Med Chem Lett 17: 3647-51 (2007) Article DOI: 10.1016/j.bmcl.2007.04.061 BindingDB Entry DOI: 10.7270/Q2JH3KV4
					More data for this Ligand-Target Pair