BDBM50212503 3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (2-pyrrolidin-1-yl-ethyl)-amide::CHEMBL234869

SMILES: COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)cc1C(=O)NCCN1CCCC1

InChI Key: InChIKey=JNSQPYRIIJRZRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50212503 (3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydro...) Show SMILES COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)cc1C(=O)NCCN1CCCC1 Show InChI InChI=1S/C30H30N4O3/c1-37-27-18-24-22(16-25(27)30(36)31-12-15-34-13-2-3-14-34)17-26-28(32-33-29(24)26)21-6-4-19(5-7-21)20-8-10-23(35)11-9-20/h4-11,16,18,35H,2-3,12-15,17H2,1H3,(H,31,36)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 mins				Bioorg Med Chem Lett 17: 3618-23 (2007) Article DOI: 10.1016/j.bmcl.2007.04.055 BindingDB Entry DOI: 10.7270/Q2DR2V6Q
					More data for this Ligand-Target Pair