null
SMILES: CN\N=c1/ccn(C2CC2)c2c(F)c(c(F)cc12)-c1cc(C)nc(C)c1
InChI Key: InChIKey=HJNSFFGNSVFZOQ-KOEQRZSOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50212604 (CHEMBL422265) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II. | Citation and Details BindingDB Entry DOI: 10.7270/Q2R49SXV | |||||||||||
More data for this Ligand-Target Pair |