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SMILES: OC1CNC(=NC1c1ccccc1)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=IDAXMZPAWQFAEJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212686   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212686
PNG
(6-phenyl-2-(4-(trifluoromethoxy)phenyl)-1,4,5,6-te...)
Show SMILES OC1CNC(=NC1c1ccccc1)c1ccc(OC(F)(F)F)cc1 |c:4|
Show InChI InChI=1S/C17H15F3N2O2/c18-17(19,20)24-13-8-6-12(7-9-13)16-21-10-14(23)15(22-16)11-4-2-1-3-5-11/h1-9,14-15,23H,10H2,(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
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Article
PubMed
 7.35E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair