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SMILES: FC(F)(F)Oc1ccc(cc1)C1=NCCCC(N1)c1ccccc1

InChI Key: InChIKey=WVZIJRDHBAWNCW-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212689   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212689
PNG
((Z)-7-phenyl-2-(4-(trifluoromethoxy)phenyl)-4,5,6,...)
Show SMILES FC(F)(F)Oc1ccc(cc1)C1=NCCCC(N1)c1ccccc1 |t:12|
Show InChI InChI=1S/C18H17F3N2O/c19-18(20,21)24-15-10-8-14(9-11-15)17-22-12-4-7-16(23-17)13-5-2-1-3-6-13/h1-3,5-6,8-11,16H,4,7,12H2,(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 4.20E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair