BDBM50212726 CHEMBL337666

SMILES: Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc\c2=N/N)C1CC1

InChI Key: InChIKey=LQLJPJIOOGJXRA-LFVJCYFKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase II (Homo sapiens (Human))	BDBM50212726 (CHEMBL337666) Show SMILES Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc\c2=N/N)C1CC1 Show InChI InChI=1S/C19H18F2N4/c1-10-7-12(8-11(2)23-10)17-15(20)9-14-16(24-22)5-6-25(13-3-4-13)19(14)18(17)21/h5-9,13H,3-4,22H2,1-2H3/b24-16+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.				Citation and Details BindingDB Entry DOI: 10.7270/Q2R49SXV
					More data for this Ligand-Target Pair