BDBM50213095 (1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidinyl)cyclohexane::CHEMBL375475

SMILES: O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12

InChI Key: InChIKey=OCJAMRRVVABJIC-VXKWHMMOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50213095 ((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human heart sodium channel Nav1.5 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily D member 2 (Rattus norvegicus)	BDBM50213095 ((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv4.2 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213095 ((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50213095 ((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human potassium channel Kv1.5 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair