BDBM50213239 7-Hydroxy-2-[4'-methoxy-3'-(3-methylbut-2-enyl)phenyl]chroman-4-one::7-hydroxy-2-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]chroman-4-one::CHEMBL229789
SMILES: [#6]-[#8]-c1ccc(cc1-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-1-[#6]-[#6](=O)-c2ccc(-[#8])cc2-[#8]-1
InChI Key: InChIKey=FPCMTBOAYZALFY-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 19A1 (Homo sapiens (Human)) | BDBM50213239 (7-Hydroxy-2-[4'-methoxy-3'-(3-methylbut-2-enyl)phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human aromatase | J Med Chem 50: 2799-806 (2007) Article DOI: 10.1021/jm070109i BindingDB Entry DOI: 10.7270/Q2668F0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM50213239 (7-Hydroxy-2-[4'-methoxy-3'-(3-methylbut-2-enyl)phe...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chosun University Curated by ChEMBL | Assay Description Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 mins | Bioorg Med Chem 19: 3378-83 (2011) Article DOI: 10.1016/j.bmc.2011.04.037 BindingDB Entry DOI: 10.7270/Q2DF6RKT | |||||||||||
More data for this Ligand-Target Pair |