BDBM50213473 CHEMBL397387::N-((1R,2S)-2-hydroxycyclohexyl)-5,6-dip-tolylpyrazine-2-carboxamide

SMILES: Cc1ccc(cc1)-c1ncc(nc1-c1ccc(C)cc1)C(=O)N[C@@H]1CCCC[C@@H]1O

InChI Key: InChIKey=PPYVHWBOOKXYEF-IRLDBZIGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50213473 (CHEMBL397387 | N-((1R,2S)-2-hydroxycyclohexyl)-5,6...) Show SMILES Cc1ccc(cc1)-c1ncc(nc1-c1ccc(C)cc1)C(=O)N[C@@H]1CCCC[C@@H]1O Show InChI InChI=1S/C25H27N3O2/c1-16-7-11-18(12-8-16)23-24(19-13-9-17(2)10-14-19)27-21(15-26-23)25(30)28-20-5-3-4-6-22(20)29/h7-15,20,22,29H,3-6H2,1-2H3,(H,28,30)/t20-,22+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to human CB1 receptor				Bioorg Med Chem Lett 17: 3978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.04.087 BindingDB Entry DOI: 10.7270/Q2FN15XR
					More data for this Ligand-Target Pair