null

SMILES: C[C@H](CNCc1ccc(cc1)-c1nnn[nH]1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1c(F)cccc1C(F)(F)F

InChI Key: InChIKey=VALATONXOTZEAD-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50213651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213651 ((S)-1-(3-(1-(4-(1H-tetrazol-5-yl)benzylamino)propa...) Show SMILES C[C@H](CNCc1ccc(cc1)-c1nnn[nH]1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1c(F)cccc1C(F)(F)F Show InChI InChI=1S/C35H35F4N7O/c1-20-13-21(2)15-25(14-20)33-32(22(3)17-40-18-23-7-9-24(10-8-23)34-42-44-45-43-34)27-19-46(12-11-30(27)41-33)31(47)16-26-28(35(37,38)39)5-4-6-29(26)36/h4-10,13-15,22,40-41H,11-12,16-19H2,1-3H3,(H,42,43,44,45)/t22-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHR				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50213651 ((S)-1-(3-(1-(4-(1H-tetrazol-5-yl)benzylamino)propa...) Show SMILES C[C@H](CNCc1ccc(cc1)-c1nnn[nH]1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1c(F)cccc1C(F)(F)F Show InChI InChI=1S/C35H35F4N7O/c1-20-13-21(2)15-25(14-20)33-32(22(3)17-40-18-23-7-9-24(10-8-23)34-42-44-45-43-34)27-19-46(12-11-30(27)41-33)31(47)16-26-28(35(37,38)39)5-4-6-29(26)36/h4-10,13-15,22,40-41H,11-12,16-19H2,1-3H3,(H,42,43,44,45)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair