null

SMILES: C[C@H](CNCCC1CCOCC1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1C(F)(F)F

InChI Key: InChIKey=QBZQELMSTKBNER-XMMPIXPASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213655 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...) Show SMILES C[C@H](CNCCC1CCOCC1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C34H42F3N3O2/c1-22-16-23(2)18-27(17-22)33-32(24(3)20-38-12-8-25-10-14-42-15-11-25)28-21-40(13-9-30(28)39-33)31(41)19-26-6-4-5-7-29(26)34(35,36)37/h4-7,16-18,24-25,38-39H,8-15,19-21H2,1-3H3/t24-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHR				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213655 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...) Show SMILES C[C@H](CNCCC1CCOCC1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C34H42F3N3O2/c1-22-16-23(2)18-27(17-22)33-32(24(3)20-38-12-8-25-10-14-42-15-11-25)28-21-40(13-9-30(28)39-33)31(41)19-26-6-4-5-7-29(26)34(35,36)37/h4-7,16-18,24-25,38-39H,8-15,19-21H2,1-3H3/t24-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GnRHR in rat pituitary cells assessed as inhibition of GnRH-stimulated LH release				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50213655 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(tetrahydro-...) Show SMILES C[C@H](CNCCC1CCOCC1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C34H42F3N3O2/c1-22-16-23(2)18-27(17-22)33-32(24(3)20-38-12-8-25-10-14-42-15-11-25)28-21-40(13-9-30(28)39-33)31(41)19-26-6-4-5-7-29(26)34(35,36)37/h4-7,16-18,24-25,38-39H,8-15,19-21H2,1-3H3/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair