BDBM50213739 7-chloro-3-cyclopentylamino-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL233552

SMILES: Oc1cc(Cl)cc2c1N=C(NC1CCCC1)NS2(=O)=O

InChI Key: InChIKey=LNGVBGYRFRMOBK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213739   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50213739 (7-chloro-3-cyclopentylamino-1,1-dioxo-1,4-dihydro-...) Show SMILES Oc1cc(Cl)cc2c1N=C(NC1CCCC1)NS2(=O)=O |t:9| Show InChI InChI=1S/C12H14ClN3O3S/c13-7-5-9(17)11-10(6-7)20(18,19)16-12(15-11)14-8-3-1-2-4-8/h5-6,8,17H,1-4H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR				Bioorg Med Chem Lett 17: 3864-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.011 BindingDB Entry DOI: 10.7270/Q21C1WKG
					More data for this Ligand-Target Pair