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BDBM50213758 7-bromo-3-(2-bromo-phenylamino)-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL396411

SMILES: Oc1cc(Br)cc2c1N=C(Nc1ccccc1Br)NS2(=O)=O

InChI Key: InChIKey=VNDBWCAKDZRRNY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213758   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50213758
PNG
(7-bromo-3-(2-bromo-phenylamino)-1,1-dioxo-1,4-dihy...)
Show SMILES Oc1cc(Br)cc2c1N=C(Nc1ccccc1Br)NS2(=O)=O
Show InChI InChI=1S/C13H9Br2N3O3S/c14-7-5-10(19)12-11(6-7)22(20,21)18-13(17-12)16-9-4-2-1-3-8(9)15/h1-6,19H,(H2,16,17,18)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR


Bioorg Med Chem Lett 17: 3864-7 (2007)

More data for this
Ligand-Target Pair