BDBM50213759 7-chloro-1,1-dioxo-3-o-tolylamino-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL233960

SMILES: Cc1ccccc1NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1

InChI Key: InChIKey=PTBVCMUKXIAPNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50213759 (7-chloro-1,1-dioxo-3-o-tolylamino-1,4-dihydro-1lam...) Show SMILES Cc1ccccc1NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1 |t:9| Show InChI InChI=1S/C14H12ClN3O3S/c1-8-4-2-3-5-10(8)16-14-17-13-11(19)6-9(15)7-12(13)22(20,21)18-14/h2-7,19H,1H3,(H2,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR				Bioorg Med Chem Lett 17: 3864-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.011 BindingDB Entry DOI: 10.7270/Q21C1WKG
					More data for this Ligand-Target Pair