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BDBM50213766 3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL233551

SMILES: CC[C@@H](C)NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1

InChI Key: InChIKey=IKXYXQRSNDYULD-ZCFIWIBFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50213766
PNG
(3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihy...)
Show SMILES CC[C@@H](C)NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1 |t:5|
Show InChI InChI=1S/C11H14ClN3O3S/c1-3-6(2)13-11-14-10-8(16)4-7(12)5-9(10)19(17,18)15-11/h4-6,16H,3H2,1-2H3,(H2,13,14,15)/t6-/m1/s1
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UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR


Bioorg Med Chem Lett 17: 3864-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.011
BindingDB Entry DOI: 10.7270/Q21C1WKG
More data for this
Ligand-Target Pair