BDBM50213766 3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL233551

SMILES: CC[C@@H](C)NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1

InChI Key: InChIKey=IKXYXQRSNDYULD-ZCFIWIBFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50213766 (3-((R)-sec-butylamino)-7-chloro-1,1-dioxo-1,4-dihy...) Show SMILES CC[C@@H](C)NC1=Nc2c(O)cc(Cl)cc2S(=O)(=O)N1 |t:5| Show InChI InChI=1S/C11H14ClN3O3S/c1-3-6(2)13-11-14-10-8(16)4-7(12)5-9(10)19(17,18)15-11/h4-6,16H,3H2,1-2H3,(H2,13,14,15)/t6-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPR				Bioorg Med Chem Lett 17: 3864-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.011 BindingDB Entry DOI: 10.7270/Q21C1WKG
					More data for this Ligand-Target Pair