BDBM50213794 CHEMBL7690

SMILES: Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1cccc(O)c1O)c2=O)C1CC1

InChI Key: InChIKey=BOEGJNXAOUQVNO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase II (Homo sapiens (Human))	BDBM50213794 (CHEMBL7690) Show SMILES Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1cccc(O)c1O)c2=O)C1CC1 Show InChI InChI=1S/C26H22F2N2O3/c1-13-8-16(9-14(2)29-13)22-20(27)11-19-24(23(22)28)30(18-6-7-18)12-17(25(19)32)10-15-4-3-5-21(31)26(15)33/h3-5,8-9,11-12,18,31,33H,6-7,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 (KDR)				Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3HJW
					More data for this Ligand-Target Pair