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SMILES: Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1c(O)cc(O)cc1O)c2=O)C1CC1

InChI Key: InChIKey=RFDGFRCCZHJVEL-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213803   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha/2-beta


(Homo sapiens (Human))		BDBM50213803
PNG
(CHEMBL428339)
Show SMILES Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1c(O)cc(O)cc1O)c2=O)C1CC1
Show InChI InChI=1S/C26H22F2N2O4/c1-12-5-14(6-13(2)29-12)23-20(27)10-19-25(24(23)28)30(16-3-4-16)11-15(26(19)34)7-18-21(32)8-17(31)9-22(18)33/h5-6,8-11,16,31-33H,3-4,7H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
n/an/an/an/a 98n/an/an/an/a


TBA

Assay Description
Inhibitory activity against HeLa cell Topoisomerase II

Citation and Details

BindingDB Entry DOI: 10.7270/Q2TX3HJW
More data for this
Ligand-Target Pair