BDBM50213805 CHEMBL7877

SMILES: Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1ccc(O)cc1O)c2=O)C1CC1

InChI Key: InChIKey=HXINQQSEPMANNI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50213805 (CHEMBL7877) Show SMILES Cc1cc(cc(C)n1)-c1c(F)cc2c(c1F)n(cc(Cc1ccc(O)cc1O)c2=O)C1CC1 Show InChI InChI=1S/C26H22F2N2O3/c1-13-7-16(8-14(2)29-13)23-21(27)11-20-25(24(23)28)30(18-4-5-18)12-17(26(20)33)9-15-3-6-19(31)10-22(15)32/h3,6-8,10-12,18,31-32H,4-5,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against HeLa cell Topoisomerase II				Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3HJW
					More data for this Ligand-Target Pair