BDBM50213868 CHEMBL3349449
SMILES: CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)\C=N\O)c(SC(C)(C)C)c2c1
InChI Key: InChIKey=ZDQYPEKXSXAFLC-STBIYBPSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50213868 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-Lipoxygenase/5-lipoxygenase activating protein
(Homo sapiens (Human)) | BDBM50213868
(CHEMBL3349449)Show SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)\C=N\O)c(SC(C)(C)C)c2c1 Show InChI InChI=1S/C27H35ClN2OS/c1-18(2)20-10-13-23-22(14-20)25(32-26(3,4)5)24(15-27(6,7)17-29-31)30(23)16-19-8-11-21(28)12-9-19/h8-14,17-18,31H,15-16H2,1-7H3/b29-17+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophils |
Bioorg Med Chem Lett 6: 1547-1552 (1996)
Article DOI: 10.1016/S0960-894X(96)00271-5
BindingDB Entry DOI: 10.7270/Q2DF6R6W |
More data for this
Ligand-Target Pair | |
5-Lipoxygenase/5-lipoxygenase activating protein
(Homo sapiens (Human)) | BDBM50213868
(CHEMBL3349449)Show SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)\C=N\O)c(SC(C)(C)C)c2c1 Show InChI InChI=1S/C27H35ClN2OS/c1-18(2)20-10-13-23-22(14-20)25(32-26(3,4)5)24(15-27(6,7)17-29-31)30(23)16-19-8-11-21(28)12-9-19/h8-14,17-18,31H,15-16H2,1-7H3/b29-17+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophils |
Bioorg Med Chem Lett 6: 1547-1552 (1996)
Article DOI: 10.1016/S0960-894X(96)00271-5
BindingDB Entry DOI: 10.7270/Q2DF6R6W |
More data for this
Ligand-Target Pair | |
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