BDBM50213931 CHEMBL250854::tylophorinidine

SMILES: COc1ccc2c3[C@H](O)[C@@H]4CCCN4Cc3c3cc(OC)c(O)cc3c2c1

InChI Key: InChIKey=CMFIDYCYVJWPPL-PGRDOPGGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50213931 (CHEMBL250854 | tylophorinidine) Show SMILES COc1ccc2c3[C@H](O)[C@@H]4CCCN4Cc3c3cc(OC)c(O)cc3c2c1 Show InChI InChI=1S/C22H23NO4/c1-26-12-5-6-13-14(8-12)15-9-19(24)20(27-2)10-16(15)17-11-23-7-3-4-18(23)22(25)21(13)17/h5-6,8-10,18,22,24-25H,3-4,7,11H2,1-2H3/t18-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 17: 4338-42 (2007) Article DOI: 10.1016/j.bmcl.2007.05.021 BindingDB Entry DOI: 10.7270/Q2HD7VBW
					More data for this Ligand-Target Pair