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BDBM50213936 (S)-2,3,6,7-tetramethoxy-8b,9,10,11,12,12a-hexahydro-9a-aza-cyclopenta[b]triphenylene::CHEMBL399317

SMILES: COc1cc2C3CN4CCC[C@H]4C=C3c3cc(OC)c(OC)cc3-c2cc1OC

InChI Key: InChIKey=AVTCXJVXWDPCND-PVCZSOGJSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50213936
PNG
((S)-2,3,6,7-tetramethoxy-8b,9,10,11,12,12a-hexahyd...)
Show SMILES COc1cc2C3CN4CCC[C@H]4C=C3c3cc(OC)c(OC)cc3-c2cc1OC |w:5.5,c:13|
Show InChI InChI=1S/C24H27NO4/c1-26-21-9-16-15-8-14-6-5-7-25(14)13-20(15)19-12-24(29-4)23(28-3)11-18(19)17(16)10-22(21)27-2/h8-12,14,20H,5-7,13H2,1-4H3/t14-,20?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>300n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assay


Bioorg Med Chem Lett 17: 4338-42 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.021
BindingDB Entry DOI: 10.7270/Q2HD7VBW
More data for this
Ligand-Target Pair