BDBM50214030 (1S,3S)-N1-(3,4-dichlorobenzyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine::CHEMBL250123

SMILES: COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc3ccc(Cl)c(Cl)c3)nc2c1

InChI Key: InChIKey=FHCNKAAOBUPAHQ-ROUUACIJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50214030 ((1S,3S)-N1-(3,4-dichlorobenzyl)-N3-(7-methoxy-4-me...) Show SMILES COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc3ccc(Cl)c(Cl)c3)nc2c1 Show InChI InChI=1S/C24H27Cl2N3O/c1-15-10-24(29-23-13-19(30-2)7-8-20(15)23)28-18-5-3-4-17(12-18)27-14-16-6-9-21(25)22(26)11-16/h6-11,13,17-18,27H,3-5,12,14H2,1-2H3,(H,28,29)/t17-,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Mölndal Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4232-41 (2007) Article DOI: 10.1016/j.bmcl.2007.05.034 BindingDB Entry DOI: 10.7270/Q27W6BVC
					More data for this Ligand-Target Pair