BDBM50214198 2-{4-n-hexyloxy-3-[(4-trifluoromethylbenzoylamino)methyl]phenylmethyl}butyric acid::CHEMBL229831

SMILES: CCCCCCOc1ccc(CC(CC)C(O)=O)cc1CNC(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HXLPZGNZHMZDIY-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50214198 (2-{4-n-hexyloxy-3-[(4-trifluoromethylbenzoylamino)...) Show SMILES CCCCCCOc1ccc(CC(CC)C(O)=O)cc1CNC(=O)c1ccc(cc1)C(F)(F)F |w:12.11| Show InChI InChI=1S/C26H32F3NO4/c1-3-5-6-7-14-34-23-13-8-18(15-19(4-2)25(32)33)16-21(23)17-30-24(31)20-9-11-22(12-10-20)26(27,28)29/h8-13,16,19H,3-7,14-15,17H2,1-2H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARdelta transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50214198 (2-{4-n-hexyloxy-3-[(4-trifluoromethylbenzoylamino)...) Show SMILES CCCCCCOc1ccc(CC(CC)C(O)=O)cc1CNC(=O)c1ccc(cc1)C(F)(F)F |w:12.11| Show InChI InChI=1S/C26H32F3NO4/c1-3-5-6-7-14-34-23-13-8-18(15-19(4-2)25(32)33)16-21(23)17-30-24(31)20-9-11-22(12-10-20)26(27,28)29/h8-13,16,19H,3-7,14-15,17H2,1-2H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARalpha transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50214198 (2-{4-n-hexyloxy-3-[(4-trifluoromethylbenzoylamino)...) Show SMILES CCCCCCOc1ccc(CC(CC)C(O)=O)cc1CNC(=O)c1ccc(cc1)C(F)(F)F |w:12.11| Show InChI InChI=1S/C26H32F3NO4/c1-3-5-6-7-14-34-23-13-8-18(15-19(4-2)25(32)33)16-21(23)17-30-24(31)20-9-11-22(12-10-20)26(27,28)29/h8-13,16,19H,3-7,14-15,17H2,1-2H3,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Effect on PPARgamma transactivation activity in HEK293 cells				Bioorg Med Chem 15: 5177-90 (2007) Article DOI: 10.1016/j.bmc.2007.05.023 BindingDB Entry DOI: 10.7270/Q2QZ29P7
					More data for this Ligand-Target Pair