BDBM50214236 (S)-N-(5-(3-(1,3-bis(3,4-dimethoxyphenyl)propan-2-ylamino)-2-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide::CHEMBL428584

SMILES: COc1ccc(CC(Cc2ccc(OC)c(OC)c2)NC[C@@H](O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC

InChI Key: InChIKey=WRXCIXZVWQRAMR-QHCPKHFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50214236 ((S)-N-(5-(3-(1,3-bis(3,4-dimethoxyphenyl)propan-2-...) Show SMILES COc1ccc(CC(Cc2ccc(OC)c(OC)c2)NC[C@@H](O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC Show InChI InChI=1S/C29H38N2O8S/c1-36-26-10-7-19(16-28(26)38-3)12-22(13-20-8-11-27(37-2)29(17-20)39-4)30-18-23(32)14-21-6-9-25(33)24(15-21)31-40(5,34)35/h6-11,15-17,22-23,30-33H,12-14,18H2,1-5H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]iodocyanopindolol from cloned human adrenergic beta-3 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 4290-6 (2007) Article DOI: 10.1016/j.bmcl.2007.05.030 BindingDB Entry DOI: 10.7270/Q2M61JZT
					More data for this Ligand-Target Pair