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SMILES: CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)[C@H](CNc2nccs2)NC1=O

InChI Key: InChIKey=XPFHPJPMHWXZHD-CMTIAEDTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214273   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Motilin receptor


(Homo sapiens (Human))		BDBM50214273
PNG
((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-8-(propan-2...)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)[C@H](CNc2nccs2)NC1=O
Show InChI InChI=1S/C31H39ClN6O4S/c1-20(2)27-30(41)37-25(19-36-31-35-14-16-43-31)28(39)34-12-6-9-22-8-3-4-11-26(22)42-15-13-33-24(29(40)38-27)18-21-7-5-10-23(32)17-21/h3-5,7-8,10-11,14,16-17,20,24-25,27,33H,6,9,12-13,15,18-19H2,1-2H3,(H,34,39)(H,35,36)(H,37,41)(H,38,40)/t24-,25+,27-/m1/s1
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 41n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]-motilin from human motilin receptor expressed in CHO cells

Bioorg Med Chem Lett 17: 4187-90 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.043
BindingDB Entry DOI: 10.7270/Q2GF0T62
More data for this
Ligand-Target Pair