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SMILES: CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(c2)C(F)(F)F)NCCOc2ccccc2CCCNC(=O)[C@H](Cn2nnnc2C)NC1=O

InChI Key: InChIKey=MQZRKGFBDTZMAW-CMTIAEDTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214274   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Motilin receptor


(Homo sapiens (Human))		BDBM50214274
PNG
((5R,8R,11S)-11-[(5-methyl-1H-1,2,3,4-tetrazol-1-yl...)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(c2)C(F)(F)F)NCCOc2ccccc2CCCNC(=O)[C@H](Cn2nnnc2C)NC1=O
Show InChI InChI=1S/C31H39F3N8O4/c1-19(2)27-30(45)37-25(18-42-20(3)39-40-41-42)28(43)36-13-7-10-22-9-4-5-12-26(22)46-15-14-35-24(29(44)38-27)17-21-8-6-11-23(16-21)31(32,33)34/h4-6,8-9,11-12,16,19,24-25,27,35H,7,10,13-15,17-18H2,1-3H3,(H,36,43)(H,37,45)(H,38,44)/t24-,25+,27-/m1/s1
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 21n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]-motilin from human motilin receptor expressed in CHO cells

Bioorg Med Chem Lett 17: 4187-90 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.043
BindingDB Entry DOI: 10.7270/Q2GF0T62
More data for this
Ligand-Target Pair