BDBM50214375 3',6'-dihydroxy-N-[2-(4-methanesulfonamidophenoxy)ethyl]-N-[2-(4-methanesulfonamidophenyl)ethyl]-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxamide::CHEMBL390300

SMILES: CS(=O)(=O)Nc1ccc(CCN(CCOc2ccc(NS(C)(=O)=O)cc2)C(=O)c2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc23)cc1

InChI Key: InChIKey=UHWSRTCNJLGXHE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50214375 (3',6'-dihydroxy-N-[2-(4-methanesulfonamidophenoxy)...) Show SMILES CS(=O)(=O)Nc1ccc(CCN(CCOc2ccc(NS(C)(=O)=O)cc2)C(=O)c2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc23)cc1 Show InChI InChI=1S/C39H35N3O11S2/c1-54(47,48)40-26-6-3-24(4-7-26)17-18-42(19-20-51-30-12-8-27(9-13-30)41-55(2,49)50)37(45)25-5-14-32-31(21-25)38(46)53-39(32)33-15-10-28(43)22-35(33)52-36-23-29(44)11-16-34(36)39/h3-16,21-23,40-41,43-44H,17-20H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG expressed in HEK293 cells by SPA				J Med Chem 50: 2931-41 (2007) Article DOI: 10.1021/jm0700565 BindingDB Entry DOI: 10.7270/Q2736RR2
					More data for this Ligand-Target Pair