null

SMILES: N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1

InChI Key: InChIKey=BKQJCMOVBFAIQR-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50214439 (CHEMBL227170 | octanedioic acid {2'-[2-amino-3-(4-...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 Show InChI InChI=1S/C29H34N4O5/c30-25(19-20-11-17-23(34)18-12-20)29(37)32-26-8-6-5-7-24(26)21-13-15-22(16-14-21)31-27(35)9-3-1-2-4-10-28(36)33-38/h5-8,11-18,25,34,38H,1-4,9-10,19,30H2,(H,31,35)(H,32,37)(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50214439 (CHEMBL227170 | octanedioic acid {2'-[2-amino-3-(4-...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 Show InChI InChI=1S/C29H34N4O5/c30-25(19-20-11-17-23(34)18-12-20)29(37)32-26-8-6-5-7-24(26)21-13-15-22(16-14-21)31-27(35)9-3-1-2-4-10-28(36)33-38/h5-8,11-18,25,34,38H,1-4,9-10,19,30H2,(H,31,35)(H,32,37)(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36.9	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50214439 (CHEMBL227170 | octanedioic acid {2'-[2-amino-3-(4-...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 Show InChI InChI=1S/C29H34N4O5/c30-25(19-20-11-17-23(34)18-12-20)29(37)32-26-8-6-5-7-24(26)21-13-15-22(16-14-21)31-27(35)9-3-1-2-4-10-28(36)33-38/h5-8,11-18,25,34,38H,1-4,9-10,19,30H2,(H,31,35)(H,32,37)(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50214439 (CHEMBL227170 | octanedioic acid {2'-[2-amino-3-(4-...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 Show InChI InChI=1S/C29H34N4O5/c30-25(19-20-11-17-23(34)18-12-20)29(37)32-26-8-6-5-7-24(26)21-13-15-22(16-14-21)31-27(35)9-3-1-2-4-10-28(36)33-38/h5-8,11-18,25,34,38H,1-4,9-10,19,30H2,(H,31,35)(H,32,37)(H,33,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50214439 (CHEMBL227170 | octanedioic acid {2'-[2-amino-3-(4-...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 Show InChI InChI=1S/C29H34N4O5/c30-25(19-20-11-17-23(34)18-12-20)29(37)32-26-8-6-5-7-24(26)21-13-15-22(16-14-21)31-27(35)9-3-1-2-4-10-28(36)33-38/h5-8,11-18,25,34,38H,1-4,9-10,19,30H2,(H,31,35)(H,32,37)(H,33,36)/t25-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42.1	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assay				J Med Chem 50: 3054-61 (2007) Article DOI: 10.1021/jm070178x BindingDB Entry DOI: 10.7270/Q26W99SW
					More data for this Ligand-Target Pair