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BDBM50214447 3-(2-(3-acetamidophenylamino)-8-cyanopyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-N,N-diethylbenzamide::CHEMBL230886

SMILES: CCN(CC)C(=O)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1

InChI Key: InChIKey=SMQHLZPDQJHUAF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214447   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II alpha


(Homo sapiens (Human))
BDBM50214447
PNG
(3-(2-(3-acetamidophenylamino)-8-cyanopyrazolo[1,5-...)
Show SMILES CCN(CC)C(=O)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1
Show InChI InChI=1S/C25H25N9O2/c1-4-33(5-2)23(36)17-8-6-9-19(12-17)30-25-32-24(31-22-18(14-26)15-27-34(22)25)29-21-11-7-10-20(13-21)28-16(3)35/h6-13,15H,4-5H2,1-3H3,(H,28,35)(H2,29,30,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
370n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair