BDBM50214454 CHEMBL230462::N-(3-(8-cyano-4-(cyclobutylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)phenyl)acetamide

SMILES: CC(=O)Nc1cccc(Nc2nc(NC3CCC3)n3ncc(C#N)c3n2)c1

InChI Key: InChIKey=FJBWNYUATWULDT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50214454 (CHEMBL230462 | N-(3-(8-cyano-4-(cyclobutylamino)py...) Show SMILES CC(=O)Nc1cccc(Nc2nc(NC3CCC3)n3ncc(C#N)c3n2)c1 Show InChI InChI=1S/C18H18N8O/c1-11(27)21-14-6-3-7-15(8-14)22-17-24-16-12(9-19)10-20-26(16)18(25-17)23-13-4-2-5-13/h3,6-8,10,13H,2,4-5H2,1H3,(H,21,27)(H2,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polaris Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human CK2 alpha				Bioorg Med Chem Lett 17: 4191-5 (2007) Article DOI: 10.1016/j.bmcl.2007.05.041 BindingDB Entry DOI: 10.7270/Q23778D9
					More data for this Ligand-Target Pair