BDBM50214455 CHEMBL395968::N-(3-(8-cyano-4-(4-(piperazin-1-ylmethyl)phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)phenyl)acetamide

SMILES: CC(=O)Nc1cccc(Nc2nc(Nc3ccc(CN4CCNCC4)cc3)n3ncc(C#N)c3n2)c1

InChI Key: InChIKey=JTOGLXNEHDOISW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50214455 (CHEMBL395968 | N-(3-(8-cyano-4-(4-(piperazin-1-ylm...) Show SMILES CC(=O)Nc1cccc(Nc2nc(Nc3ccc(CN4CCNCC4)cc3)n3ncc(C#N)c3n2)c1 Show InChI InChI=1S/C25H26N10O/c1-17(36)29-21-3-2-4-22(13-21)30-24-32-23-19(14-26)15-28-35(23)25(33-24)31-20-7-5-18(6-8-20)16-34-11-9-27-10-12-34/h2-8,13,15,27H,9-12,16H2,1H3,(H,29,36)(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polaris Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human CK2 alpha				Bioorg Med Chem Lett 17: 4191-5 (2007) Article DOI: 10.1016/j.bmcl.2007.05.041 BindingDB Entry DOI: 10.7270/Q23778D9
					More data for this Ligand-Target Pair