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BDBM50214462 CHEMBL230987::N-(3-(8-cyano-4-(3-ethoxyphenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)phenyl)acetamide

SMILES: CCOc1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1

InChI Key: InChIKey=ZDSIIYNOURJMOC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214462   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II alpha


(Homo sapiens (Human))
BDBM50214462
PNG
(CHEMBL230987 | N-(3-(8-cyano-4-(3-ethoxyphenylamin...)
Show SMILES CCOc1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(cnn23)C#N)c1
Show InChI InChI=1S/C22H20N8O2/c1-3-32-19-9-5-8-18(11-19)27-22-29-21(28-20-15(12-23)13-24-30(20)22)26-17-7-4-6-16(10-17)25-14(2)31/h4-11,13H,3H2,1-2H3,(H,25,31)(H2,26,27,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
190n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair