BindingDB PrimarySearch

BDBM50214527 4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazolidin-3-yl)methyl)benzoic acid::4-[5-(4-benzyloxybenzylidene)-2,4-dioxothiazolidin-3-yl]methylbenzoic acid::CHEMBL235595

SMILES: OC(=O)c1ccc(CN2C(=O)S\C(=C/c3ccc(OCc4ccccc4)cc3)C2=O)cc1

InChI Key: InChIKey=BCWFPQLVRPXRGU-HMAPJEAMSA-N

Data: 9 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50214527
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human PTP1B				Bioorg Med Chem 16: 7399-409 (2008) Article DOI: 10.1016/j.bmc.2008.06.014 BindingDB Entry DOI: 10.7270/Q2PC325T
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of LAR (unknown origin)				Bioorg Med Chem 16: 7399-409 (2008) Article DOI: 10.1016/j.bmc.2008.06.014 BindingDB Entry DOI: 10.7270/Q2PC325T
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Saccharomyces cerevisiae)	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae low molecular weight Protein-tyrosine phosphatase Ltp1				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human T cell protein-tyrosine phosphatase				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human protein-tyrosine phosphatase 1B				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human leukocyte antigen related protein-tyrosine phosphatase				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human protein-tyrosine phosphatase beta				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human low molecular weight Protein-tyrosine phosphatase IF2				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50214527 (4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of human low molecular weight Protein-tyrosine phosphatase IF1				Bioorg Med Chem 15: 5137-49 (2007) Article DOI: 10.1016/j.bmc.2007.05.027 BindingDB Entry DOI: 10.7270/Q2QR4XXH
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair