BDBM50214562 2-(3-(4'-hydroxybiphenyl-4-yl)-7-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-6-yloxy)propane-1,3-diol::2-[3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-2,4-dihydro-indeno[1,2-c]pyrazol-6-yloxy]-propane-1,3-diol::CHEMBL248194

SMILES: COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)cc1OC(CO)CO

InChI Key: InChIKey=YPVUJZZWOGFNPI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50214562 (2-(3-(4'-hydroxybiphenyl-4-yl)-7-methoxy-1,4-dihyd...) Show SMILES COc1cc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)cc1OC(CO)CO Show InChI InChI=1S/C26H24N2O5/c1-32-23-12-21-18(11-24(23)33-20(13-29)14-30)10-22-25(27-28-26(21)22)17-4-2-15(3-5-17)16-6-8-19(31)9-7-16/h2-9,11-12,20,29-31H,10,13-14H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Chk1				J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8
					More data for this Ligand-Target Pair