BDBM50214686 1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one::1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-fluorophenyl]piperazin-1-yl}-1-(2,4-dichlorobenzyl)-2-oxoethyl]pyrrolidin-2-one::CHEMBL236732

SMILES: CC(C)C[C@H](N)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O

InChI Key: InChIKey=NUALMFMLNXDIHK-AZGAKELHSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50214686 (1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...) Show SMILES CC(C)C[C@H](N)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O Show InChI InChI=1S/C28H35Cl2FN4O2/c1-18(2)14-24(32)22-17-21(31)7-8-25(22)33-10-12-34(13-11-33)28(37)26(35-9-3-4-27(35)36)15-19-5-6-20(29)16-23(19)30/h5-8,16-18,24,26H,3-4,9-15,32H2,1-2H3/t24-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from MC4R receptor in HEK293 cells				Bioorg Med Chem 15: 5166-76 (2007) Article DOI: 10.1016/j.bmc.2007.05.026 BindingDB Entry DOI: 10.7270/Q2FF3S2P
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50214686 (1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...) Show SMILES CC(C)C[C@H](N)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O Show InChI InChI=1S/C28H35Cl2FN4O2/c1-18(2)14-24(32)22-17-21(31)7-8-25(22)33-10-12-34(13-11-33)28(37)26(35-9-3-4-27(35)36)15-19-5-6-20(29)16-23(19)30/h5-8,16-18,24,26H,3-4,9-15,32H2,1-2H3/t24-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity at human MC4R				Bioorg Med Chem Lett 17: 5610-3 (2007) Article DOI: 10.1016/j.bmcl.2007.07.097 BindingDB Entry DOI: 10.7270/Q2XK8F8V
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50214686 (1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-fluor...) Show SMILES CC(C)C[C@H](N)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O Show InChI InChI=1S/C28H35Cl2FN4O2/c1-18(2)14-24(32)22-17-21(31)7-8-25(22)33-10-12-34(13-11-33)28(37)26(35-9-3-4-27(35)36)15-19-5-6-20(29)16-23(19)30/h5-8,16-18,24,26H,3-4,9-15,32H2,1-2H3/t24-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of microsomal CYP3A4				Bioorg Med Chem Lett 17: 5610-3 (2007) Article DOI: 10.1016/j.bmcl.2007.07.097 BindingDB Entry DOI: 10.7270/Q2XK8F8V
					More data for this Ligand-Target Pair