BDBM50214748 CHEMBL103007
SMILES: Cc1cn(Cc2ccc(Cl)cc2)c2cc(ccc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl
InChI Key: InChIKey=SCIDSYICJROITB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 4 (Homo sapiens (Human)) | BDBM50214748 (CHEMBL103007) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Affinity for rolipram binding site of phosphodiesterase type IV (PDE4) | Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 4 (Homo sapiens (Human)) | BDBM50214748 (CHEMBL103007) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of phosphodiesterase type IV (PDE4) activity | Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6 | |||||||||||
More data for this Ligand-Target Pair |